When and how should multiple imputation be used for handling. With a slight abuse of the terminology, we will use the term imputation to mean the data where missing values are replaced with one set of plausible values. Additionally, complete case analysis can have a severe negative effect on the power by greatly reducing. How to use spssreplacing missing data using multiple imputation regression method duration. Simple techniques to pool and save multiple imputed data.
This is because many statistics that are required for postestimation are not easily defined in a multiple imputation context. Citeseerx stata multipleimputation reference manual release. This tells stata how the multiply imputed data is to be stored once the imputation has been completed. Multipleimputation reference manual, stata release 16.
The article illustrates how to perform mi by using amelia package in a clinical scenario. An alternative to cca is multiple imputation mi, which creates m copies of the data set, replacing the missing values in each data set with independent random draws from the predictive distribution of the missing values under a specific model the imputation model. The checklist presented in table 1 is a suggested guide for planning the multiple imputation project. The validity of multipleimputationbased analyses relies on the use of an appropriate model to impute the missing values. In the appendix it is explained how exactly the procedures can be carried out in sas 9. What is important is the choice of the proper imputation model, which involves a number of considerations that cannot be mapped out here. For longitudinal data as well as other data, mi is implemented following a framework for estimation and inference based upon a three step process. Mice operates under the assumption that given the variables used in the imputation procedure, the missing data are missing at random mar, which means that the probability that a value is missing depends only on observed values and not on. When and how should multiple imputation be used for. If you have stata 11 or higher the entire manual is available as a pdf file. Stata bookstore multipleimputation reference manual. A multilevel model is used to deal with the dependence of the data. An imputation represents one set of plausible values for missing data, and so multiple imputations represent multiple sets of plausible values. Me stata multilevel mixedeffects reference manual mi stata multiple imputation reference manual mv stata multivariate statistics reference manual pss stata power and samplesize reference manual p stata programming reference manual sem stata structural equation modeling reference manual svy stata survey data reference manual st.
Multiple imputation provides a useful strategy for dealing with data sets with missing values. Glm with multiple imputation or mixed model cross validated. Multiple imputation of missing data for multilevel models. Amelia package is powerful in that it allows for mi for time series data. Before version 11, analysis of such data was possible with the help of ados. But it is safe to surmise that in most cases a chained equation imputation will be required. Note that the number of postestimation commands after mi estimation is quite restricted compared to the vast array that is usually offered by stata. In this method the imputation uncertainty is accounted for by creating these multiple datasets. Missing data takes many forms and can be attributed to many causes.
Statas documentation consists of over 14,000 pages detailing each feature in stata including the. The procedure outlined in this paper should also be of assistance to any sas or stata user who intends to use multiple imputation in this context. Multiple imputation mi is a powerful alternative to complete case analysis that has several advantages. A simulation study of a linear regression with a response y and two predictors x1 and x 2 was performed on data with n 50, 100 and 200 using complete cases or multiple imputation with 0, 10, 20, 40 and 80. Multiple imputation originated in the early 1970s, and has gained increasing popularity over the years. Stata press, a division of statacorp llc, publishes books, manuals, and journals about stata and general statistics topics for professional researchers of all disciplines. The stata mi imputation command generated 20 sets of complete data for each individual. Mice operates under the assumption that given the variables used in the imputation procedure, the missing data are missing at random mar, which means that the probability that a value is missing depends only on observed values and. Datasets for stata multipleimputation reference manual, release 15. Feb 26, 2018 note that the number of postestimation commands after mi estimation is quite restricted compared to the vast array that is usually offered by stata.
Multiple imputation is a simulationbased statistical technique for handling missing data. It should be used within a multiple imputation sequence since missing values are imputed stochastically rather than deterministically. However, the imputed values are assumed to be the real values that would have been observed when the data would have been complete. Multiple imputation has become very popular as a generalpurpose method for handling missing data. In multiple imputation, the imputatin process is repeated multiple times resulting in multiple imputed datasets.
Mi stata multipleimputation reference manual mv stata multivariate statistics reference manual pss stata power and samplesize reference manual p. How can i perform multiple imputation on longitudinal data. Theoretical considerations as well as simulation studies have shown that the inclusion of auxiliary variables is generally of benefit. In order to use these commands the dataset in memory must be declared or mi set as mi dataset. Complex tests with multiply imputed data require special commands. In stata, just as you declare the data to be svyset, you declare it to be an mi multiple imputation dataset. Actually, with the help of stata the practical difficulties in most cases are minor. Mi is becoming an increasingly popular method for sensitivity analyses in order to assess the impact of missing data.
Sccm using multiple imputation to avoid bias from missing. Jan 01, 2014 the procedure outlined in this paper should also be of assistance to any sas or stata user who intends to use multiple imputation in this context. So, you need an mlm or gee, or perhaps some other method that deals with the dependence. Sometimes this includes writing temporary files in the current working directory.
Use the fastest disk space available to you, both for your data set and for the working directory. Auxiliary variables in multiple imputation in regression. Here, you will declare the fpl variables to be imputed. Apr 01, 20 discover how to use stata s multiple imputation features for handling missing data. Simple techniques to pool and save multiple imputed data in stata. Checklist of issues and considerations for the multiple imputation process. View homework help multiple imputation stata from econ 281 at northwestern university. Stata press 4905 lakeway drive college station, tx 77845, usa 979. Every installation of stata includes all the documentation in pdf format. Click on a filename to download it to a local folder on your. Multiple imputation has emerged as an appropriate and flexible way of handling missing data.
When there is missing data, the default results are often obtained with complete case analysis using only observations with complete data can produce biased results though not always. Part 2 implementing multiple imputation in stata and spss carol b. Multiple imputation sexp deptp anxtp gsitp depts anxts gsits. Mice is a particular multiple imputation technique raghunathan et al.
Multiple imputation mi without considering time trend of a variable may cause it to be unreliable. A statistical programming story chris smith, cytel inc. Bootstrap inference when using multiple imputation 3 with multiple imputation for particular analyses. This is a simple example and there are other commands and different ways to do multiple. Introduction in large datasets, missing values commonly occur in several variables. Jun 03, 2017 how to use spssreplacing missing data using multiple imputation regression method duration. Assume a joint multivariate normal distribution of all variables. Multiple imputation is a common approach to addressing missing data issues. However, things seem to be a bit trickier when you actually want to do some model selection e. Multiple imputation and model selection cross validated. Datasets for stata multipleimputation reference manual, release 15 datasets used in the stata documentation were selected to demonstrate how to use stata.
Datasets for stata multipleimputation reference manual. The validity of multiple imputation based analyses relies on the use of an appropriate model to impute the missing values. Paul allison, one of my favorite authors of statistical information for researchers, did a study that showed that the most common method actually gives worse results that listwise deletion. The multiple imputation process contains three phases. The chained equation approach to multiple imputation. Often, the analyst is tempted to rush into multiple imputation without a complete understanding of the missing data problem and associated issues. Implementing multiple imputation in stata and spss carol b. Stata manual for multipleimputation available from help menu pdf. We can never be completely certain about imputed values.
My dataset of 2 people have 10 variable with some missing observations. Some datasets have been altered to explain a particular feature. Multiple imputation mi is one of the principled methods for dealing with missing data. In part 1 we cover how to impute a single continuous variable with regres. Single imputation methods iris eekhout missing data. Discover how to use statas multiple imputation features for handling missing data. If you want to be a regular participant in statalist, i suggest that you change your username to your full real name, as requested in the registration page and faq you can do it with the contact us button at the bottom of the page. Feb 24, 2011 the chained equation approach to multiple imputation. Multiple imputation involves more reading and writing to disk than most stata commands. In this paper, we provide an overview of currently.
This statement is manifestly false, disproved by the ucla example of svy estimation following mi impute chained. Datasets used in the stata documentation were selected to demonstrate how to use stata. Multiple imputation of bootstrap samples has been implemented in the analyses ofbriggs et al. Completecase methods, which simply discard observations with any missing data, generally make the usually unrealistic assumption that the data are mcar, or at least mar within categories defined by the variables included in the analysis model. Multiple imputation stata stata multipleimputation. In addition, multilevel models have become a standard tool for analyzing the nested data structures that result when lower level units e. Most multiple imputation methods assume multivariate normality, so a common question is how to impute missing values from categorical variables. Multiple imputation for time series data with amelia package. For data analysis, this command often is a composite prefix mi which is followed by a standard stata command. Statas documentation consists of over 14,000 pages detailing each feature in stata including the methods and formulas and fully worked examples.
This example is adapted from pages 114 of the stata 12 multiple imputation manual which i highly recommend reading and also quotes directly from the stata 12 online help. Thermuohp biostatistics resource channel 211,660 views 45. This series is intended to be a practical guide to the technique and its implementation in stata, based on the questions sscc members are asking the ssccs statistical. Despite the widespread use of multiple imputation, there are few guidelines available for checking imputation models. Stata has a suite of multiple imputation mi commands to help users not only impute their data but also explore the patterns of missingness present in the data. Multiple imputation is a robust and flexible option for handling missing data.
Stata module to impute missing values using the hotdeck method, statistical software components s366901, boston college department of economics, revised 02 sep 2007. Multiple imputation reference manual, stata release 16. Missing data in stata centre for multilevel modelling, 20 1 introduction to the youth cohort study dataset you will be analysing data from the youth cohort study of england and wales ycs1. Multiple imputation is fairly straightforward when you have an a priori linear model that you want to estimate. Multiple imputation is becoming increasingly popular. Here, analysis of multiply imputed data is achieved by commands that start with mi.